biomarkers sst2  (R&D Systems)

Journal: medRxiv

Article Title: Soluble suppression of tumorigenicity-2 (sST2) predicts mortality and right heart failure in LVAD patients

doi: 10.1101/2023.02.06.23285564

Figure Lengend Snippet: Kaplan–Meier survival of patients with a normal or elevated pre-operative soluble suppression of tumorigenicity-2 (sST2) level.

Article Snippet: Opfermann et al. showed a significant increase in sST2 during the initial post-operative period after LVAD implantation and normalization to pre-operative levels after one week and normal levels after three weeks. ( ) Although repeated sST2 measurements appeared to be a strong predictor of outcome in patients with acute HF , the predictive value of serially measured sST2 levels in LVAD patients on long term outcomes has not been elucidated yet.

Techniques:

Journal: medRxiv

Article Title: Soluble suppression of tumorigenicity-2 (sST2) predicts mortality and right heart failure in LVAD patients

doi: 10.1101/2023.02.06.23285564

Figure Lengend Snippet: Trajectory of post-operative soluble suppression of tumorigenicity-2 (sST2) levels in four patients. The black dots indicate the sST2 measurement, and the predicted sST2 trajectory by the linear mixed effects model is depicted by the colored line for patients (A and B) without event (A and B) or patients that reached the primary endpoint (C and D).

Article Snippet: Opfermann et al. showed a significant increase in sST2 during the initial post-operative period after LVAD implantation and normalization to pre-operative levels after one week and normal levels after three weeks. ( ) Although repeated sST2 measurements appeared to be a strong predictor of outcome in patients with acute HF , the predictive value of serially measured sST2 levels in LVAD patients on long term outcomes has not been elucidated yet.

Techniques:

Journal: medRxiv

Article Title: Soluble suppression of tumorigenicity-2 (sST2) predicts mortality and right heart failure in LVAD patients

doi: 10.1101/2023.02.06.23285564

Figure Lengend Snippet: Heatmap for death or urgent heart transplantation (A) and right heart failure (B) of all post-operative soluble suppression of tumorigenicity-2 (sST2) levels, sorted by highest value. The triangle (▼) indicates urgent heart transplantation, the circle (Ο) indicates death and the asterisk (*) indicates right heart failure.

Article Snippet: Opfermann et al. showed a significant increase in sST2 during the initial post-operative period after LVAD implantation and normalization to pre-operative levels after one week and normal levels after three weeks. ( ) Although repeated sST2 measurements appeared to be a strong predictor of outcome in patients with acute HF , the predictive value of serially measured sST2 levels in LVAD patients on long term outcomes has not been elucidated yet.

Techniques: Transplantation Assay

Journal: medRxiv

Article Title: Soluble suppression of tumorigenicity-2 (sST2) predicts mortality and right heart failure in LVAD patients

doi: 10.1101/2023.02.06.23285564

Figure Lengend Snippet:

Article Snippet: Opfermann et al. showed a significant increase in sST2 during the initial post-operative period after LVAD implantation and normalization to pre-operative levels after one week and normal levels after three weeks. ( ) Although repeated sST2 measurements appeared to be a strong predictor of outcome in patients with acute HF , the predictive value of serially measured sST2 levels in LVAD patients on long term outcomes has not been elucidated yet.

Techniques: